CHiCAGO is released!

We are finally ready to release CHiCAGO, our pipeline for Capture HiC analysis. Led by Jonathan, Paula and Mikhail, and a result of two years of work, this package features a new statistical model and a bespoke multiple testing procedure for calling significant interactions in these challenging data. A preprint describing the algorithm in detail will be available in the next few weeks, but the software and documentation are ready to use!

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The medaka population genomics paper is out

Mikhail’s paper on the population genetics parameters of wild medaka fish is out in G3. This was part of a large collaboration involving the teams of Ewan Birney at EMBL-EBI, Jochen Wittbrodt and his very talented student Tom Auer at Uni Heidelberg, Felix Loosli in Karlsruhe, and last but not least Kiyoshi Naruse at NIBB (Okasaki, Japan). This work lays the foundation for establishing a population genomics resource in medaka fish (similar to DGRP in Drosophila and 1000 genomes in humans).

Ewan Birney wrote a nice guest blog post on this project at Haldan’s Sieve when we submitted the first preprint of our story to ArXiv.

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Hashem joins us

Hashem Koohy has joined the group, moving on from a postdoc with Tim Hubbard at Sanger Institute and two (!) PhD studies (one in pure maths and one in bioinformatics). Hashem will be co-supervised by Peter Fraser and other PIs from the Nuclear Dynamics ISP. Hashem’s main focus will be on the Systems Biology of Ageing Programme that is carried out jointly by our ISP, but he also has plans for some other exciting projects on the side. Welcome!

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